The difference between weather<span> and </span>climate<span> is a measure of time. </span>Weather<span> is what conditions of the atmosphere are over a short period of time, and</span>climate<span> is how the atmosphere "behaves" over relatively long periods of time.</span>
the are puppets that have human emotions
Answer;
-Inactivation; limited
Differentiation requires inactivation of particular genes to produce populations with limited capabilities that form tissues.
Explanation;
-Cell differentiation is how generic embryonic cells become specialized cells. This occurs through a process called gene expression.
-Gene expression is the specific combination of genes that are turned on or off (expressed or repressed), and this is what dictates how a cell functions.
-Gene expression plays a critical role in the morphological changes that take place in a developing embryo and fetus and in the differentiation of stem cells to form specialized cells.
<span>Lafora disease is the most severe teenage-onset progressive epilepsy, a unique form of glycogenosis with perikaryal accumulation of an abnormal form of glycogen, and a neurodegenerative disorder exhibiting an unusual generalized organellar disintegration. The disease is caused by mutations of the EPM2A gene, which encodes two isoforms of the laforin protein tyrosine phosphatase, having alternate carboxyl termini, one localized in the cytoplasm (endoplasmic reticulum) and the other in the nucleus. To date, all documented disease mutations, including the knockout mouse model deletion, have been in the segment of the protein common to both isoforms. It is therefore not known whether dysfunction of the cytoplasmic, nuclear, or both isoforms leads to the disease. In the present work, we identify six novel mutations, one of which, c.950insT (Q319fs), is the first mutation specific to the cytoplasmic laforin isoform, implicating this isoform in disease pathogenesis. To confirm this mutation's deleterious effect on laforin, we studied the resultant protein's subcellular localization and function and show a drastic reduction in its phosphatase activity, despite maintenance of its location at the endoplasmic reticulum.
I got my information from </span>https://www.ncbi.nlm.nih.gov/pubmed/14722920
Answer: Ice cores.
Explanation: Ice cores are commonly studied by scientists to find out what the climate was like decades and centuries ago.
