Adenylate cyclases (ACs) are the membrane-bound glycoproteins that convert ATP to cAMP and pyrophosphate.
When activated by G-protein Gs, adenylate cyclases (ACs), which are membrane-bound glycoproteins, catalyze the synthesis of cAMP from ATP.
Different AC isoforms are widely expressed in various tissues that participate in regulatory systems in response to particular stimuli.
Humans have 9 different AC isoforms, with AC5 and AC6 thought to be particularly important for cardiac activities.
Nitric oxide has an impact on the activity of AC6, hence the protein's nitrosylation may control how it works. However, little is known about the structural variables that affect nitrosylation in ACs and how they relate to G's.
We predict the cysteines that are prone to nitrosylation using this 3D model, and we use virtual ligand screening to find potential new AC6 ligands.
According to our model, the AC-Gs interface's Cys174 in G's and Cys1004 in AC6 (subunit C2) are two potential residues that could experience reversible nitrosylation.
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Answer:
What role do transcription factors play in gene structure and function?
Transcription factors are proteins that bind to the upstream regulatory elements of genes in the promoter and enhancer regions of DNA and stimulate or inhibit gene expression and protein synthesis. They play critical roles in embryogenesis and development
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Explanation:
infectious diseases can spread in a variety of ways: through the air, from direct or indirect contact with another person, soiled objects, skin or mucous membrane, saliva, urine, blood and body secretions, through sexual contact, and through contaminated food and water.
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Answer:
The correct answer would be "Can prevent genetic diseases".
Cloning refers to the process of making an identical copy of organism, cell or DNA fragments.
One of the applications of cloning is eradication or prevention of genetic diseases.
It is done by isolating the correct or functional gene and make copies of it in in-vitro conditions.
The gene or DNA fragment is then inserted back into the cell.
With advancement in cloning process and understanding of stem cells, cloning process also favors tissues and organ harvesting which also help in reducing diseases.
