Answer and explanation;
-The insulin receptor itself has decreased kinase activity leading to fewer binding sites for singling effectors to become activated.
Therefore; the signaling effectors are less likely to be activated.
-Additionally,, feedback inhibition decreases signaling effector binding to receptor.
-The lack of activation of these initial signaling effectors prevents any subsequent steps from happening.
-We can thus conclude this by saying that higher insulin concentrations are necessary to obtain the same level of signaling leading to physiological effects that would exist in someone without type-2 diabetes.
-Also the requirement for higher insulin concentration means that the cells that respond to insulin are resistant to its effect.
Interphase:
-the cell replicates its chromosomes
-each chromosome has two sister chromatids held together by a centromere
Prophase 1 chromosomes coil up and a spindle forms
-homologous chromosomes come together matched gene by gene forming a tetrad
-Crossing Over may occur when chromatids exchange genetic material
-this occurs two or three times per pair of homologous chromosomes
-Crossing Over results in new combinations of alleles on a chromosomes
Metaphase 1:
-the centromere of each chromosome becomes attached to a spindle fiber
-the spindle fibers pull the tetrads to the equator of the spindle
-homologous chromosomes are lined up side by side as tetrads
Anaphase 1:
-homologous chromosomes separate and move to opposite ends of the cell
-centromeres do not split
-this ensures that each new cell will receive only one chromosome from each homologous
pair
Telophase 1:
-the spindle breaks down and the chromosomes uncoil
-the cytoplasm divides to yield two new cells
-each cell has half the genetic information of the original cell because it has only one homologous
chromosome from each pair
Prophase II-
-a spindle forms in each of the two new cells and the fibers attach to the chromosomes
Metaphase II-
-the chromosomes are pulled to the center of the cell and line up randomly at the equator
Anaphase II-
-the centromere of each chromosome splits the sister chromatids separate and move to opposite poles
Telophase II nuclei re form the spindles break down the cytoplasm divides identical to mitosis (Meiosis II)
What Meiosis produces four haploid sex cells from one original diploid cell each haploid cell contains one chromosome from each homologous pair haploid cells will become gametes transmitting genes to offspring
I hope this helps
The object is balanced against standard units of mass
Answer:
This is technology.
Explanation:
Generally both science and technology are instrumental to emergence of developed humanity and the environment.Why science is concerned with the emergence of knowledge,the manoeuvre and the practical application of the knowledge for innovations to change and improve the world around is called Technology.
The application of technology for improvement of humanity has wide application.From Healthcare in genetic engineering,Biomedical sciences, telemedcine,robotic surgery,to Agriculture to boost food production,cloning of crops and animals and production of pest and herbicide resistant products.
In construction for roads,and building of houses,fitted with AC and FAN for maximum comfort
Besides the application in field of engineering for power generation in petroleum, communication, entertainment,printing,warfare and transportation are few of other means where technology has improved humanity
