use PEMDAS
The numbers in the absolute value symbols are what you need to solve first:
I2-4(3-6)I
I2-4(-3)I simplify the parentheses
I2+12I multiply -4 and -3
I14I add the terms 2 and 12
14 simplify 14 with the absolute value symbols
Now solve what's on the outside of the absolute value symbols:
23-2
21 subtract and simplify 23 and -2
Finally, multiply the two terms we have made, 14 and 21:
14 * 21 = 294
Your final answer should be 294.