I think it’s A
I think so because the Synovial membrane acts as a lubricator, much like how oil lubricated the joints of the tin man. If the lubricants were removed, the friction would increase as there is no oil to decrease the friction and let the bones function properly
The circadian clock is most sensitive to light from about 2 hours before usual bedtime and through the night, until about 1 hour after usual wake-up in the morning (this is the sensitive period). Exposure to light during these times will affect when your body naturally gets sleepy and is ready to fall asleep.
Garrod hypothesized that "inborn errors of metabolism" such as alkaptonuria occur because...genes dictate the production of specific enzymes, and affected individuals have genetic defects that cause them to lack certain enzymes.
Explanation:
Archibald Garrod researched on alkaptonuria and proposed the ‘one gene-one enzyme’ hypothesis. This led to the finding that alkaptonuria is caused due to an inherited or “inborn error of metabolism”.
This hypothesis stated that each gene codes and responsible for a single specific enzyme which facilitates a particular step in the metabolic processes.
According to Garrod, a mutation of a particular gene leads to specific error or defect leading to a lack of a particular enzyme that takes part in the biochemical metabolic pathways. This disrupts the metabolic pathway at the specific enzymatic action point.
In alkaptonuria, it was found that the defective phenotype of dark urine is due to the inborn error happening during the waste elimination process.