Sickle-cell anemia is caused by a point mutation in the β-globin chain of hemoglobin, causing the hydrophilic amino acid glutamic acid to be replaced with the hydrophobic<span> amino acid valine at the sixth position.</span>
Change in single nucleotide of the DNA is referred to as point mutation. In hemoglobin, point mutation replaces the "adenine base" by "thymine" at the 17th nucleotide of the hemoglobin beta gene. This single nucleotide mutation replace the codon GAG (glutamic acid) to GTG (which encodes amino acid valine) and causes sickle cell anemia.
As long as this is the same question asked previously, the car will move towards the right, because the forces pushing it in that direction are greater in total than the other forces.
