They exist in all the cells of the body. They are inherited via sperm and egg cells.
They will not be inherited unless a similar damage has happened in eggs or sperms due to the same exposure to mutagen, In that case, progeny might show the mutation.
But they are an inherited mutation that was supported in fertilization of the egg during reproduction.
Glucose breaks down to pyruvate in the cell cytoplasm upon signal by the hormone insulin in the presence of excess glucose in the blood system through the glycolytic pathway
