Cocaine has been prepared by a sequence beginning with a Mannich reaction between dimethyl acetonedicarboxylate, methylamine, an
d butanedial. The mechanism involves the following steps: 1. Following initial protonation of the carbonyl oxygen, nucleophilic attack by the amine forms carbinolamine 1; 2. Proton transfer and elimination of water forms iminium ion 2; 3. The enol form of the dicarboxylate ester attacks the iminium ion to form adduct 3; 4. Adduct 3 tautomerizes to form enol 4; 5. Following protonation of the aldehyde, cyclization occurs as protonated carbinolamine 5 is formed; 6. Proton transfer and elimination of water lead to iminium ion 6; 7. The enol attacks the iminium ion in a second cyclization reaction to form bicyclic ion 7; 8. Deprotonation leads to the final product. Write out the mechanism on a separate sheet of paper and then draw the structure of protonated carbinolamine 1.
1 answer:
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Answer:
44.2 L
Explanation:
Use Charles Law:
We have all the values except for V₂; this is what we're solving for. Input the values:
- make sure that your temperature is in Kelvin
From here, we need to get V₂ by itself. To do this, multiply by 273 on both sides:
Therefore, V₂ = 44.2 L
It's also helpful to know that temperature and volume are linearly related. So, when temperature drops, so will volume and vice versa.
696.32 mmHg is the final pressure of the gas.
<h3>What is an ideal gas equation?</h3>The ideal gas equation, pV = nRT, is an equation used to calculate either the pressure, volume, temperature or number of moles of a gas.
Given data:
= 720 mmHg
= ?
= 2.5 mol
= 3.2 mol
= 34 L
= 45 L
Formula
Combined gas law
= 696.32 mmHg
Hence, 696.32 mmHg is the final pressure of the gas.
Learn more about an ideal gas equation here:
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