Answer is: the discovery of sub atomic particles like electrons.
J. J. Thomson discovered the electron in 1897.
His "plum pudding" model (1904) suggested: the electrons are embedded in the positive charge.
With this model, he abandoned his earlier hypothesis (the atom was composed of immaterial vortices).
J.J. Thomson placed two oppositely charged electric plates around the cathode ray. He did experiments using different metals as electrode materials and found that the properties of the cathode ray remained constant no matter what cathode material he used.
Tomson concluded that atoms are divisible and that the corpuscles are their building blocks (atoms are made up of smaller particles).
The Mass Number is the combination of the amount of Protons and Neutrons in an element, so if the total mass is 222, and the amount of protons is 86, then you can do 86 + x = 222 to find that x is equal to 136