Answer:
the central dogma of biology is: that all cells execute replication, transcription, and translation to maintain their genetic information and convert it in gene products. Now, coronavirus breaks it by not following the process on DNA and jumping to RNA:
Explanation:
There are two main reasons for this answer. The first one is that all genetic cells that want to preserve their genetic information to create genetic products. Follow a process in which they have to go through the three stages we have presented before and then they create genetic products or materials using RNA as a source. However, In coronavirus case, it doesn't follow them and jump to RNA directly without using DNA as a breach to create genetic products and find their genetic configuration on RNA instead of using it as a source of energy.
Answer:
Instead of physically trapping drugs into vesicles, amphiphilic phospholipids in pharmacosomes are complexed with drugs via hydrogen bonds between active hydrogens and phospholipids. The drug molecule bearing an active hydrogen atom (-COOH, -OH, -NH2 etc.) can be converted to an ester with the hydroxyl moiety of the lipid, resulting in an amphiphilic complex that aids membrane, tissue, or cell wall transfer. The drug-lipid complex exists as a monomer at low concentrations, but a variety of structures (e.g. micelles, colloidal or hexagonal shape) might develop when the concentration increases. Eventually, the conjugated drug will be released from pharmacosomes upon chemical or enzymatic hydrolysis. Compared to other liposomal drug delivery systems, pharmacosomes have advantages such as minimized drug degradation and increased drug bioavailability. For example, limitations in transfersomes such as predisposition to oxidative degradation and impurity of natural phospholipids can be overcome by pharmacosomes. Besides, other advantages are also beneficial in various research:
No drug leakage due to the covalently link.
High entrapment efficiency.
Suitable for both hydrophilic and lipophilic drugs.
Improved bioavailability especially in case of poorly soluble drugs.
No need to remove unentrapped drugs from the formulation as needed in case of liposomes.
Reduction in adverse effects, toxicity, and the cost of therapy.
Avoid drug incorporation in the body of the patient.
Membrane fluidity does not affect drug release.
Explanation:
https://www.creative-biostructure.com/Pharmacosomes-Production-615.htm
TRUE- The Lord said to the serpent “because you have done this, cursed are you above all livestock and all wild animals.”