Answer: Thrombus Formation
Explanation:
Atherosclerosis is a chronic, progressive disease in which the plaques starts building in the walls of artery. These plaques are the deposition of the cholesterol and other lipids, calcium and inflammatory cells known as macrophages.
Once these substances starts depositing in the artery it can lead to thrombus formation which is not cured by itself.
The Atherosclerosis is the predisposes to the thrombus formation which can cause myocardial ischemia.
Agonist/antagonist
Agonist are drugs that bind and activate a receptor with effecting the response.If the effect results in maximum response it is considered as full agonist. However if the drug that binds to the receptor results only into partial efficacy in relation to the full activation of the receptor, this is considered as partial agonist.
Antagonist are drugs that blocks a biologic response of a hormone or another drug. They usually have affinity to the receptors but has no efficacy. This drug will just inhibit the activation of the receptors by the aganist.