The State of California uses a mechanism known as "NOTS" to rehabilitate chronic violators of driving laws. The Negligent Operator Treatment System (NOTS) is based on negligent operator points and consists of a computer-generated series of warning letters and progressive sanctions against the driving privilege.
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The process that connects glycolysis and the citric acid cycle is the acetyl CoA formation.
Glucuronidation, a conjugation reaction, is thought to protect the liver by both reducing hepatic BA toxicity and increasing their urinary elimination. The present study evaluates the contribution of each process in the overall BA detoxification by glucuronidation.
