Muscles bones no on organs and no on skin
Answer:
A tiny sense positively charge core called a nucleus in which nearly all the mass is concentratedm
For a closed system, you need two things:
1) a conservation of mass within the boundaries of the system
2) the ability to freely exchange energy to & from the "closed" system with a surrounding external system
So, the answer is <u><em>never</em></u>, since your defining the "system" as the water within the bathtub, and an open bathtub is exposed to evaporation, which is not conserving mass within the defined "system".