Answer:
1. The difference between the normal hemoglobin protein DNA sequence and the sickle cell hemoglobin DNA sequence is a base to base shift, in this case adenine (GAG) to thymine (GTG).
2. The difference affects the amino acid sequence of the protein by replacing glutamic acid (Glu) with valine (Val).
Explanation:
In sickle cell anemia, a change in the DNA nucleotide sequence is observed, where adenine is substituted by thymine, whose expression is the change in the amino acid sequence of globine β, incorporating valine instead of glutamic acid. This represents a molecular mutation - point mutation - by subtitution, which corresponds to missense mutation.
<u>Normal hemoglobin protein in a RBC</u>
DNA CTG ACT CCT GAG GAG AAG TCT
Amino acids Leu Thr Pro Glu Glu Lys Ser
<u>Sickle cell hemoglobin protein in a RBC</u>
DNA CTG ACT CCT <em>GTG</em> GAG AAG TCT
Amino acids Leu Thr Pro <em>Val</em> Glu Lys Ser
When GAG is transcribed to mRNA, the CUC codon is obtained, which codes for glutamic acid. Thymine substitution causes the DNA sequence to change to GTG, which is transcribed as CAC, the codon that encodes the amino acid valine. The <u>change from glutamic acid to valine in β-globin causes an altered hemoglobin, giving the abnormal erythrocytes observed in sickle cell disease</u>.
Answer:
the corret answer is the sun
Explanation:
The Sun is the major source of energy for organisms and the ecosystems of which they are a part. Producers such as plants, algae, and cyanobacteria use the energy from sunlight to make organic matter from carbon dioxide and water.
Find the attachment for the answer.
Note: I have added the complete question in the attachment.
Answer:
Index fossils
Explanation:
The index fossils are the fossils that come in very handy for the geologists when it comes to identifying or dating rock samples or other fossils. The reason for this is that the index fossils have already been dated. They are fossils that are very commonly found, wide dispersed, are easy to be identified, and are limited to only a certain geological period. These characteristics make them an excellent indicator for the dating of the rock layers in which they are found, or the fossils found in the same layers with them, without conducting further examinations.
Answer:
C. <em>Clostridium</em> and <em>Bacillus</em>.
Explanation:
<em>Bacillus </em>and <em>Clostridium</em> are the gram-positive bacteria and form endospores. Endospores are the resistant dormant structures formed by some gram-positive bacteria.
These bacteria form the endospores within their vegetative cells. The endospores are highly resistant to environmental stress conditions and make these bacterial genera the dangerous pathogens.
