Answer:
Maybe that your question is incomplete, in the options following the statement listed none is correct ...
The procedures would have the following order:
1-Propionyl-CoA is converted to Methylmalonyl-CoA thanks to the enzyme Porpionyl-Carboxylase CoA which adheres to a carboxyl modifying the chemical structure (This enzyme depends on ATP, biotin and bicarbonate, to carry out the reaction).
2-Then, Methylmelanolyl-CoA is adhered to a radical, thanks to the enzyme methylmalonyl-CoA racemase, thus generating (R) -methylmalonyl-CoA as a product of the reaction.
3- And finally, (R) -methylmalonyl-CoA is converted to succinyl-CoA, an intermediate of the tricarboxylic acid cycle, by the enzyme methylmalonyl-CoA mutase, which requires cobalamin to catalyze carbon-carbon bond migration.
4-The mechanism of the methylmalonyl-CoA mutase begins with the cleavage of the bond between the 5 'of CH2-5'-deoxyadenosyl and cobalt, which is in its 3 + (III) oxidation state, which produces a 5'-radical. deoxyadenosil and cabalamin in the state of reduced oxidation Co (II)
Explanation:
Propionyl-CoA is important to know that it can come from different biological rations of the organism, such as: beta oxidation (of odd-chain fatty acids), the metabolism of isoleucine and valine and As a product of α-ketobutyric acid, which in turn it is a product of the metabolism of threonine and methionine.
