Question

Explain how botulinum toxin alters the normal sequence of events at the neuromuscular junction to result in paralysis. Be sure to include the vesicular transport process that is inhibited.

Answer 1

At neuromuscular junctions, a neurotransmitter called as acetylcholine if found. Botulinum toxin inhibits the transmission of acetylcholine at the synaptic junctions. Botulin toxin acts at presynaptic junctions and blocks the release of acetylcholine, leading to paralysis.