Question

What was most significant about Robert Fulton’s steamboat run of 1807?

Answer 1

It showed that his new engine improved steamboat travel is the answer to your question

Answer 2

Fulton and Livingston together built the first commercial steamboat. (Then called the "North River Steamboat".) Now called the Clermont, which carried passangers between New York and Albany, New York. It showed that his new engine improved steamboat travel.