Ibuprofen, a well-known non-steroidal anti-inflammatory drug, has chirality. Only the S enantiomer has anti-inflammatory activit

Question

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Ibuprofen, a well-known non-steroidal anti-inflammatory drug, has chirality. Only the S enantiomer has anti-inflammatory activit

y (although the R enantiomer is converted slowly by the body into the S enantiomer). Add wedge-and-dash bonds to complete the perspective structures of the two stereoisomers of ibuprofen.

Chemistry

1 answer:

lorasvet [3.4K] · Answer 1 · 2021-12-24T19:06:14+03:00

Answer:

See image attached

Explanation:

Ibuprofen is a chiral compound. 'Chiral' means that it has the ability to rotate plane polarised light owing to the presence of an asymmetrically substituted carbon atom. There are two known stereoisomers of the compound; the S- stereoisomer and the R-stereoisomer. The both are shown using wedge and dash perspectives in the image attached.

Only the S- stereoisomer is active as a drug. The R-stereoisomer is gradually converted into the S-stereoisomer in the body. The drug may also be given as a racemic mixture.