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3 years ago

Compare and Contrast competitive inhibition and and Allosteric inhibition

Biology

1 answer:

gizmo_the_mogwai [7]3 years ago

3 0

Competitive inhibition vs allosteric inhibition

In competitive the substrate and inhibitor bind at the same active site - pretty straightforward. In allosteric regulation (speaking specifically about inhibition here), the inhibitor is binding at a site other than the active site, and changing the enzyme in some way to make it inactive.

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3 years ago

Cystic fibrosis is an autosomal recessive disorder. In one population, the frequency of affected individuals (A 2 A 2) is 0.0004

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Explanation:

Hardy Weinberg Equilibrium formula for allelic frequency is: $p+q=1$

Hardy Weinberg Equilibrium formula for genotypic frequency is: $p^2+q^2+2pq=1$

Here, $p$ =frequency of dominant allele

$q$ =frequency of recessive allele

$p^2$ =frequency of dominant genotype

$q^2$ =frequency of recessive genotype

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frequency of affected individuals=0.0004(given)

here,affected individuals means the one's having Cystic Fibrosis and since it is recessive disease so we can write frequency of recessive genotype as: $q^2$ =0.0004

If $q^2$ =0.0004 $q$ will be 0.02;frequency of recessive allele will be 0.02

Using the formula $p+q=1$

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hence,frequency of dominant allele will be 0.98

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