Answer:
Rough endoplasmic reticulum and Mitochondria.
Explanation:
Disulfide bonds are known as covalent bonds. They are formed by the oxidation of 2 cysteines and these bonds can provide stability to proteins. These bonds mainly formed in intermembrane space of mitochondria and cellular compartments outside the cytoplasm endoplasmic reticulum. Both of these organelles present in an oxidation state providing an atmosphere for disulfide bond formation.
Cytoplasm and Nuclei mostly exit in reducing state because of the existence of disulfide reductase which is reducing the disulfide bonds between the cysteine residue to thiolate state. So, the disulfide bond formation will not happen.
Answer:
Thymine in DNA occurs as the result of thymidylate synthase creating deoxythymidine monophosphate (dTMP), which then undergoes phosphorylation to deoxythymidine diphosphate (dTDP), then to Deoxythymidine triphosphate (dTTP), and incorporated into DNA by the DNA polymerase (DNA pol). Thymine in tRNA arises post-transcriptionally, by S-adenosylmethionine-dependent methylation of a uridine 5'-monophosphate (UMP) residue in RNA.
Explanation:
Thymidylate synthase is an enzyme involved in <em>de novo</em> DNA synthesis. This enzyme (thymidylate synthase) catalyzes the transfer of the one-carbon group from 5,10-methylene-tetrahydrofolate (5,10-CH2-THF) to deoxyuridine monophosphate (dUMP) and subsequent methylation to produce deoxythymidine monophosphate (dTMP), which is then phosphorylated to deoxythymidine triphosphate (dTTP) by kinases and incorporated into DNA. On the other hand, specific tRNA methylases catalyze the methylation of transference RNA (tRNA) by using S-adenosylmethionine as a methyl donor. Since tRNA methylation is a post-transcriptional modification, this chemical reaction is considered an epitranscriptomic modification on the RNA molecule.
OK so the phase you are looking for will be Metaphase I
