Because it is easily accessible and has a mild immune response, the retina makes a good target for gene therapy.
- In a mouse model, the inner retina was highly effectively transduced by an intravitreally injected adeno-associated virus (AAV) vector.
- The vitreous and internal limiting membrane (ILM) operated as obstacles to transduction in large animals, reducing the efficacy of retinal transduction.
- Before administering AAV vectors, we performed vitrectomy (VIT) and ILM peeling on cynomolgus monkeys to get around these obstacles.
- The findings suggest that surgical ILM peeling prior to AAV vector delivery would be beneficial for retinal disease treatment and safe for effective transduction of the nonhuman primate retina.
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Answer:
During mitosis, the nucleus divides. Mitosis is followed by cytokinesis, when the cytoplasm divides, resulting in two cells. After cytokinesis, cell division is complete. Scientists say that one parent cell, or the dividing cell, forms two genetically identical daughter cells, or the cells that divide from the parent cell. The term "genetically identical" means that each cell has an identical set of DNA, and this DNA is also identical to that of the parent cell. If the cell cycle is not carefully controlled, it can cause a disease called cancer, which causes cell division to happen too fast. A tumor can result from this kind of growth.
During mitosis, the two sister chromatids must be split apart. Each resulting chromosome is made of 1/2 of the "X". Through this process, each daughter cell receives one copy of each chromosome. Mitosis is divided into four phases:
Prophase: The chromosomes "condense," or become so tightly wound that you can see them under a microscope. The wall around the nucleus, called the nuclear envelope, disappears. Spindles also form and attach to chromosomes to help them move.
Metaphase: The chromosomes line up in the center of the cell. The chromosomes line up in a row, one on top of the next.
Anaphase: The two sister chromatids of each chromosome separate, resulting in two sets of identical chromosomes.
Telophase: The spindle dissolves and nuclear envelopes form around the chromosomes in both cells.
Answer:
Identical shape and structure.
Explanation:
Those organisms that reproduce sexually have high variations and differences between the parent and its offspring. They are not identical to each other because the offspring gains half characteristics from male parent and half from the female parent making it different from its parent. Identical feature is present in the organisms that reproduce through asexually means from only one parent so the identical shape and structure is not the cost of sexual reproduction.
Answer: synthesize RNA by following a strand of DNA. RNA polymerase is an enzyme that is responsible for copying a DNA sequence into RNA sequence, during the process of transcription
Explanation:
