Question

Which two vitamins help to lower the risk of heart disease by participating in the metabolic reaction of converting homocysteine into methionine?

Answer 1

Answer:B6 and B12.

Explanation:

Homocysteine is an amino acid produced from demethylation of methionine.The later is an amino acid needed in the body which must be conserved.

In order to conserve it ,Homocysteine is recycled in a specific pathways which inovles activities of Vitamin B6 and B12

.Therefore deficiency of these vitamins leads to elevated levels of Homocysteine.

HIGH LEVELS OF HOMOCYSTEINE AFFECT THE ENDOTHELIAL CELLS ;LEADING TO ABNORMAL CLOTTING OF BLOOD.THIS INCREASE IN BLOOD VISCOSITY PUT THE HEART AT RISK OF CARDIOVASCULAR DISEASES.

Answer 2

Answer:

Folic acid(Vitamin B9) and vitamins B12

Explanation:

To convert homocysteine into methionine, folic acid(Vitamin B9) and vitamins B6 and B12 is required.

A deficiency in these vitamins can elevate homocysteine levels which affects the endothelial cells, causes

abnormal clotting and higher CVD risks.

A higher homocysteine level is associated with an increase in ischemic heart disease.

It is noted that a dose of 0.4 to 1 mg of folic acid with vitamins B12 and B6, lowers serum homocysteine levels.