Answer:
3- Breast-feeding can reduce an infant’s risk of infection, allergies, and certain chronic diseases.
.4- All mothers should consume 500 kcal extra daily while breast-feeding until weaning of the infant.
5- Women with AIDS or active tuberculosis should feed formula rather than breast-feed.
Explanation:
Breastfeeding is also a great benefit to the environment and society, that is, it does not require the use of energy for manufacturing or create waste or air pollution. Also, there is no risk of contamination and it is always at the right temperature and ready to feed. Given the importance of breastfeeding for the health of mothers and babies, Centers for Disease Control and prevention supports breastfeeding through hospital initiatives, work-site accommodation, continuity of care and community support initiatives. Colostrum is the earliest breast-milk produced, beginning in mid-pregnancy (12-18 weeks) and is continually produced for the first few days after baby's birth, it provides all the nutrients and fluid that your newborn needs in the early days, as well as many substances to protect your baby against infections. Mothers with untreated and active tuberculosis infections are not advised to breastfeed. They may breastfeed after their infection is cured or brought under control so that it does not spread to the infant.
Yes, it is true that Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis.
Enhancer of zeste homolog 2 (EZH2), a key histone methyltransferase and EMT inducer, is overexpressed in diverse carcinomas, including breast cancer.
However, the molecular mechanisms of EZH2 dysregulation in cancers are still largely unknown. Here, we discover that EZH2 is asymmetrically dimethylated at R342 (meR342-EZH2) by PRMT1.
meR342-EZH2 was found to inhibit the CDK1-mediated phosphorylation of EZH2 at T345 and T487, thereby attenuating EZH2 ubiquitylation mediated by the E3 ligase TRAF6.
We also demonstrate that meR342-EZH2 resulted in a decrease in EZH2 target gene expression, but an increase in breast cancer cell EMT, invasion and metastasis.
Moreover, we confirm the positive correlations among PRMT1, meR342-EZH2 and EZH2 expression in the breast cancer tissues. Finally, we report that high expression levels of meR342-EZH2 predict a poor clinical outcome in breast cancer patients.
Our findings may provide a novel diagnostic target and promising therapeutic target for breast cancer metastasis.
Learn more about breast cancer here : brainly.com/question/6747562
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They have the same mass as the mass of the reactants. evidence to back this up is the law of conservation of mass