If pyruvate-2-14C (pyruvate with the middle carbon atom radioactively labeled) is provided to actively respiring mitochondria, m
ost of the radioactivity will be incorporated into citrate. Trace the route whereby radioactively labeled carbon atoms are incorporated into citrate, and indicate where in the citrate molecule the label will first appear.
The middle carbon atom of pyruvate in the TCA cycle becomes the carboxyl carbon of acetate and hence the newly added (upper) carboxyl group in citrate
Explanation:
Before entering the TCA cycle, pyruvate is converted into Acetyl-CoA by oxidative decarboxylation of pyruvate. 1st two carbons of glucose to be fully oxidized. This reaction is catalyzed by Pyruvate dehydrogenase.
The middle carbon atom of the pyruvate in the TCA cycle becomes the carboxyl carbon of the acetate as the carboxyl group is removed from the pyruvate , releasing CO2. NAD is reduced to NADH. Acetyl group is transferred to coenzyme-A , resulting in acetyl coA
When chemical communication at a synapse is terminated by the recapture of neurotransmitter molecules by the presynaptic neuron, we refer to the process as <u>Reuptake.</u>
(E) none of the above statements are true rain almost always comes from west to east so the western side of the mountain ranges would get more rain. A and C are not very relevant to the question<span />