Draw a hypothetical metabolic pathway composed of five substrates, five enzymes, and a product called Biological Sciazine. Numbe
r the substrates 1-5, and label the enzymes A-E, in order. (For instance, enzyme A catalyzes the reaction between substrates 1 and 2) a. Suppose a mutation made the gene for enzyme C nonfunctional. What molecule would accumulate in the affected cells?
b. Suppose some individuals can survive if given substrate 5 in the diet, but they die if given substrates 1, 2, 3, and 4. Which enzyme pathway is affected by this mutation?
a) The substrate 2 will be accumulated in the cells.
b) The enzyme E is mutated
Explanation:
a) The enzyme C has a mutation, the substrate 2 will not be turn into substrate 3 and this will cause to accumulation of 2.
b) when cells have 1,2,3 or 4 because of mutation of E non of these substrates cannot lead to 5. but ıf 5 gıven from the diet, the individuals can survive.
