1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
kumpel [21]
3 years ago
13

Learn how changes in binding free energy affect binding and the ratio of unbound and bound molecules.

Chemistry
1 answer:
Delvig [45]3 years ago
5 0

C)[D]/[ED] = 5.20

D)[D]/[ED] = 5.20

E)[D']_T = 1.495* 10 ^-7 M

F)[D'] / [ED']  = 0.0579

Explanation:

E = 250 nM =2.5* 10 ^-7 mol/L , T=298.15 K

Dissociation constant of K_D = 1.3 μM (1.3 *10 ^-6 M)

E + D ⇄ ED → K_a = [ED] / [D][E]   (association constant)

ED ⇄ E + D → K_D = [E][D] / [ED]  (dissociation constant)

C)

[E] =2.5*10^-7 mol/L

K_D = 1.3* 10^-6 M

K_D = [E][D] / [ED] → [D]/[ED] = K_D / [E]

= [D]/[ED] = 1.3* 10 ^-6 / 2.5 *10^-7

= 13/25 * 10

=130/25 = 5.20

[D]/[ED] = 5.20

D)

ΔG =RTln Kd

ΔG_2 for E and D = 1.987 * 298.15 * ln 1.3*10^-6

ΔG_2 592.454 * [ln 1.3 +ln 10^-6]

ΔG_1 = 592.424 [0.2623 - 13.8155]

ΔG_2 = -592.424 * 13.553

ΔG_1 = -8184.633 cal/ mol

ΔG_1 = -8184.633  * 4.18 J/mol = -34244.508 J?mol

ΔG_1 = -34.245 KL/mol

so, ΔG_2 = ΔG_1 - 10.5 KJ/mol

ΔG_2 = -34.245 - 10.5

ΔG_2 = -44.745KJ / mol

ΔG_2 =RT ln K_D

-44.745 *10^3

=8.314 *298.15 lnK_D

lnK_D' = - 44745 / 2478.81 g

ln K_D' = -18.051

K_D' = -18.051

K_D' = e^-18.051

[D]/[ED] = 5.20

E)

[E] = 2.5* 10 ^-7 mol/ L = a

K_D' = [E][D] / [ED']                                  E +D' → ED'

K_D' = a/2(x-(a/2) / (a/2)

KD' = x - a/2

=2.447 *10^-8 = (2.5/2) * 10^-7

x=2.447 * 10^-8 + 1.25 * 10^-7

x = 2.447 *10^-8 + 1.25 * 10 ^-7

x= 10^-7 [1.25 + 0.2447]

x = 1.4947 * 10^-7

[D']_T = 1.495* 10 ^-7 M

F)

K_D' = [E][D'] / [ED']

[D'] / [ED'] = KD' / [E]

[D'] / [ED'] = 1.447 *10^-8 / 2.5* 10^-7

[D'] / [ED'] = 0.5788 * 10^-1

[D'] / [ED']  = 0.0579

You might be interested in
Which can be classified as a trace fossil
dexar [7]

Trace fossils provide us with indirect evidence of life in the past, such as the footprints, tracks, burrows, borings, and feces left behind by animals, rather than the preserved remains of the body of the actual animal itself. so i would say B.

6 0
3 years ago
Read 2 more answers
Which is an example of flow of heat through conduction
JulsSmile [24]

Answer:

a metal spoon left in boiling water

Explanation:

5 0
3 years ago
3. 79,789kJ = (293k) (377kJ)
KatRina [158]

the anwser would most likely be j=0

5 0
3 years ago
In AG calculations, temperature is expressed in a. degrees Celsius. b. kelvins. c. degrees Fahrenheit, d. kilojoules.
schepotkina [342]

Answer:

The correct option is: a. degrees Celsius

Explanation:

The anion gap is the difference in the cations and anions in plasma, serum or urine, calculated from medical lab test results. It can be calculated by measuring the concentration of the anions or cations, which are expressed in millimoles/litre (mmol/L) or milliequivalents/liter (mEq/L).

The temperature in this test is expressed in degrees Celsius (°C).

6 0
3 years ago
Mass = 35g Volume = 7cm³ What is the Density?​
gizmo_the_mogwai [7]

Answer:

The answer is

<h2>5.0 g/cm³</h2>

Explanation:

The density of a substance can be found by using the formula

density =  \frac{mass}{volume}  \\

From the question

mass = 35 g

volume = 7 cm³

The density is

density =  \frac{35}{7}  \\

We have the final answer as

<h3>5.0 g/cm³</h3>

Hope this helps you

7 0
3 years ago
Other questions:
  • How do you write the formula for potassium hydroxide
    7·2 answers
  • Which of the following is not one of the four environmental spheres in which all of the Earth’s physical and natural processes o
    14·2 answers
  • Geometry and polarity of SnCl2
    6·1 answer
  • Who’s does an atom become a positively charged ion?
    12·1 answer
  • An
    9·1 answer
  • Is liquid ice-cream batter a solid, liquid, or gas?
    9·1 answer
  • A weight of 8.7 N is attached to a spring that has a spring constant of 190 N/m. How much will the spring stretch?
    9·1 answer
  • What happens when an ice cube melts in a glass of water?
    11·1 answer
  • Which of the following represents a neutralization reaction which hydrofluoric acid and sodium hydroxide(a base) react to produc
    7·1 answer
  • If the genotype of one parent is GG and the genotype of the other is gg, what is the probability that an offspring will have a G
    10·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!