The answer is epididymis.
<span>Testicles contain seminiferous tubules, in which sperm is produced, and an epididymis, in which sperm matures. Mature sperm passes through the epididymis to the vas deferens. There, it combines with a liquid secretion from the seminal vesicles and continues through the prostate gland to the urethra. Sperm containing fluid is called semen and it is ejected through the urethra.</span>
Answer/Explanation:
(1) a mutation in the coding region, resulting in an inactive protein
To check to see if there is a mutation, you could extract the DNA from the cancer cells and then perform PCR to amplify the gene of interest. You could then perform sanger sequencing and compare the sequence to the normal gene to see if a mutation is present. To test the effect of the mutation, you would want to see if an active protein has been formed.
To see if a normal sized protein has been formed, you could perform a western blot, comparing the protein band to the WT protein band. If the protein is absent or much smaller, it is likely not a functional protein.
(2) epigenetic silencing at the promoter of the gene, resulting in reduced transcription.
To check for changes in the epigenetic landscape of the promoter, you could perform chromatin immunoprecipitation by extracting the chromatin from the tumour cells and using antibodies for different chromatin marks to see what has changed between the normal cells and the tumor cells. E.g. H3K9me3, H3K27me3. You would perform a pull down with the antibody of interest and then PCR for your promoter to specifically look at changes at that gene compared to normal cells. To test DNA methylation, you could perform bisulfite sequencing.
To see how transcription is affected, you could extract RNA from the tumor and normal cells, and compare the levels of RNA between the two samples by qRT-PCR
False,
In order to start labor, estrogen increases and progesterone decreases.
Estrogens are a class of hormones that are essential for women's healthy sexual and reproductive development. They are sex hormones as well. The majority of estrogen hormones are produced by a woman's ovaries, however minor quantities are also produced in modest amounts by the adrenal glands and fat cells.
Progesterone is a member of the progestin drug class (female hormones). By lowering the level of estrogen in the uterus, it functions as a component of hormone replacement treatment. By substituting for the natural progesterone that some women lack, it helps to initiate menstruation.
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When contracted the Right Atrium pumps deoxygenated blood into the Right Ventricle below via the Tricuspid Valve.
