I’m pretty sure it’s the first option, if not I am so sorry.
Answer:
waterfall, waffle, and steak n' shake
Explanation:
BOOYAH!!
The right answer is A.
The methylation profile of DNA is not obtained when DNA sequencing is performed.
Methylation is a process that can occur in DNA especially at the cytosine level. And this has a very important role in gene expression as it is part of the epigenetic expression.
Gene methylation can induce or repress gene expression depending on the localization of methylated bases.
Answer:
DNA samples might be planted and it is possible to synthesize a nucleotide sequence to incriminate a person
Explanation:
In a criminal case, DNA evidence may be considered to be fraudulent because DNA samples might be planted around the crime scene. Moreover, specific genomic profiles of an individual stored in the database can be used to manufacture a DNA sample matching this profile without the necessity to obtain tissues of the person. In consequence, DNA evidence may be considered to be imperfect. Nonetheless, it is important to highlight that DNA evidence is one of the most important modern advances used during criminal trials, and it has proven to be a very useful (and effective) tool available in law enforcement.
Answer:
TNF-alpha is expressed as a homotrimer that exerts its activities through binding to two types of receptors: TNFR1 and TNFR2, which are transmembrane glycoproteins characterized by having an extracellular domain with 4 cysteine-rich domains (CRD 1-4) , each with 3 cysteinecysteine disulfide bonds.
Explanation:
TNF-alpha (Tumor Necrosis Factor), which has the characteristic of being a paracrine signaling ligand, is a pleiotropic cytokine that functions as a mediator of immune regulation, the inflammatory response and apoptosis in some cell types. Receptors in this family are involved, with some exceptions, in juxtacrine signaling; that is, both the ligand and the receptor are membrane proteins with extracellular domains through which signaling is established. The cellular responses promoted by TNF are initiated by its interaction with two different types of cell receptors, the type I receptor (55 kDa) and the type II receptor (75 kDa). Both types of receptors are part of the TNF receptor family, members of which include Fas antigen (apoptosis inducer, also called Apo-1 or CD95), CD27 (T-cell activation antigen), CD30 (lymphoma marker Hodgkin) and CD40 (B-cell antigen), which share the characteristic of cysteine-rich sequences in their extracellular domains. This family of cytokines generate cellular responses that include differentiation, proliferation, activation of NFκB and cell death, promoting the aggregation of receptor monomers, that is, they have a transmembrane domain that participates in the solubilization of the receptor and a domain of intracellular death that is involved in signal transduction. The binding of TNF to TNF-R1 induces a signaling cascade through its intracellular death domain, which subsequently leads to the activation of complex I (or inflammatory) of NFkB and proceeds to the transcription of anti-apoptotic genes, pro- inflammatory diseases and apoptosis complex II (caspases).
