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yarga [219]
3 years ago
7

Which of the following allosterically activates mammalian isocitrate dehydrogenase?a. ADPb. NADHc. ATPd. MalateCitrate

Chemistry
1 answer:
Bogdan [553]3 years ago
5 0

Answer:

a. ADP

Explanation:

Isocitrate dehydrogenase is an enzyme in citric acid cycle that occurs in mitochondrial matrix.

It catalyzes conversion of the isocitrate to the alpha-ketoglutarate and Carbon dioxide which occurs in a two step process.

<u>IDH is regulated allosterically by the ADP positively in the mammals and inhibited by ATP, NADH.</u>  

The enzyme, IDH will not catalyze the reaction unless there are low levels of ADP.

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What is the pH of a solution which is 0.600 M in dimethylamine ((CH3)2NH) and 0.400 M in dimethylamine hydrochloride ((CH3)2NH2C
Viefleur [7K]

Answer:

pH = 11.05

Explanation:

It is possible to answer this question using Henderson-Hasselbalch formula:

pH = pka + log₁₀ [A] / [HA⁺]

Where A in this case is weak base (dimethylamine) and conjugate acid (HA⁺) is dimethylamine hydrochloride.

As Ka= Kw / Kb = 1x10⁻¹⁴ / 7.4x10⁻⁴ = 1.35x10⁻¹¹ And pKa is -log Ka = <em>10.87 </em> pH of the solution is:

pH = 10.87 + log₁₀ [0.600] / [0.400]

<em>pH = 11.05</em>

<em></em>

I hope it helps!

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