The nurse response in related to the patient's query about feeling nauseated at the sight of meat is that this condition will go away in three months. Nausea and vomiting are included in early symptoms of pregnancy and in pregnancy the HCG (human chronic gonadotropin) levels are increased and due to this many women feel nauseated. It is normal in the first trimester and it will go away in the further pregnancy.
Number 2, sun increases basically everyday.
Answer:
TNF-alpha is expressed as a homotrimer that exerts its activities through binding to two types of receptors: TNFR1 and TNFR2, which are transmembrane glycoproteins characterized by having an extracellular domain with 4 cysteine-rich domains (CRD 1-4) , each with 3 cysteinecysteine disulfide bonds.
Explanation:
TNF-alpha (Tumor Necrosis Factor), which has the characteristic of being a paracrine signaling ligand, is a pleiotropic cytokine that functions as a mediator of immune regulation, the inflammatory response and apoptosis in some cell types. Receptors in this family are involved, with some exceptions, in juxtacrine signaling; that is, both the ligand and the receptor are membrane proteins with extracellular domains through which signaling is established. The cellular responses promoted by TNF are initiated by its interaction with two different types of cell receptors, the type I receptor (55 kDa) and the type II receptor (75 kDa). Both types of receptors are part of the TNF receptor family, members of which include Fas antigen (apoptosis inducer, also called Apo-1 or CD95), CD27 (T-cell activation antigen), CD30 (lymphoma marker Hodgkin) and CD40 (B-cell antigen), which share the characteristic of cysteine-rich sequences in their extracellular domains. This family of cytokines generate cellular responses that include differentiation, proliferation, activation of NFκB and cell death, promoting the aggregation of receptor monomers, that is, they have a transmembrane domain that participates in the solubilization of the receptor and a domain of intracellular death that is involved in signal transduction. The binding of TNF to TNF-R1 induces a signaling cascade through its intracellular death domain, which subsequently leads to the activation of complex I (or inflammatory) of NFkB and proceeds to the transcription of anti-apoptotic genes, pro- inflammatory diseases and apoptosis complex II (caspases).
The food company’s questions are best answered by a combination of survey and scientific tools. To answer questions such as ‘which cereal's box is the best color?’ and ‘which cereal tastes the best to every eater?’ as well as ‘which cereal would sell the most boxes?’, the food company would need to conduct a survey to a group of people which resembles their target group most. The result would help them in answering those questions.
However, to answer ‘Which cereal contains the most sugar?’, the food company would need to use scientific tools to measure to sugar content in the cereal. This is the answer.