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Slav-nsk [51]
3 years ago
8

Design a synthesis of acetophenone from benzene or toluene. 1275q Part 1 out of 5 Choose the best option for the nucleophile pre

cursor to acetophenone. 1275p1
Chemistry
1 answer:
Trava [24]3 years ago
5 0

Answer:

A Fridiel craft catalyst will convert benzene to acetophenone.

Permanganate catalyst can be used to convert toluene to acetophenone.

Explanation:

Benzene can be reduced to acetophenone by the addition of anhydrous aluminium chloride, AlCl₃

The mechanism is as follows:

Benzene + Acetyl choloride → acetophenone

To convert toluene to acetophenone, the following steps are necessary:

  • Oxidation of Toluene to Benzoic acid.

     This is done by refluxing toluene with alkaline potassium permanganate         (KMnO₄+ Na₂CO₃).

  • Benzoic acid is converted to Benzoyl chloride by treating with thioyl chloride and heating at about 80 ⁰C.
  • Benzoyl chloride is treated with methyl lithium to form Acetophenone.
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