Answer:
See the answer below
Explanation:
Let the disorder be represented by the allele a.
Since the disease is an autosomal recessive one, affected individuals will have the genotype aa and normal individuals will have the genotype Aa or AA.
Since the four adults are carriers, their genotypes would be Aa.
Aa x Aa
Progeny: AA 2Aa aa
Probability of being affected = 1/4
Probability of being a carrier = 1/2
Probability of not being affected = 3/4
(a) The chance that the child second child of Mary and Frank will have alkaptonuria = 1/2
(b) The chance that the third child of Sara and James will be free of the condition = 3/4
(c)
(d) If someone has no family history of the disorder, their genotype would be AA.
AA x aa
4 Aa
<em>The chance that a child with alkaptonuria will have an offspring with alkaptonuria if the child's mate has no family history </em>= 0
(e)
(f) <em>The chance that a child with alkaptonuria will have an offspring with alkaptonuria if the child's mate has no family history</em> = 0
Answer:
Drug Delivery
Explanation:
Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals. For the treatment of human diseases, nasal and pulmonary routes of drug delivery are gaining increasing importance
Hypophyseal portal system allows the hypothalamus to have direct communication with the anterior pituitary.
The hypophyseal portal system is a network of blood vessels that connects the anterior portion of the gland and hypothalamus at the base of the brain. Two capillary beds, one in the median eminence and the other in the anterior pituitary, make up the portal system. Its principal job is to swiftly transfer and exchange hormones between the anterior pituitary gland and the hypothalamic arcuate nucleus.
The cortisol, androgens, and aldosterone hormones interact with anterior pituitary gland cells via travelling through the hypophyseal portal system. Hormonal signaling through the hypophyseal portal system enables connection between these two structures.
To learn more about hypothalamus and pituitary here,
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Acetylcholine receptor locales are blocked. Acetylcholine receptors are found on the surface of muscle cells, moved in the neurotransmitter between nerve cells and muscle cells. It is ligand-gated particle channels, and, as different individuals from the "Cys-circle" ligand-gated particle channel superfamily, are made out of five protein subunits symmetrically organized like fights around a barrel.
