I would say 4. To create a hypothesis, you would need some knowledge about what you're studying. This is where prior knowledge could come in handy.
Meiosis is the cell replication of gametes (sex cells).
I think the correct answer from the choices listed above is option A. Horned toads squirt blood from their eyes as a means of evading predators. This is their final defense action which frightens their predators. Hope this answers the question. Have a nice day.