Question

Which one of the following statements holds true for the induced-fit model? Once the enzyme binds to the specific substrate molecule, no structural changes can occur in the active site of the enzyme. Once the enzyme binds to the specific substrate molecule, structural changes can occur in the active site to accomodate the product. Once the enzyme binds to a specific substrate molecule, subtle structure changes occur in the active site, which are reverted when the reaction is over. NextReset

Answer 1

Once the enzyme binds to the specific substrate molecule, structural changes can occur in the active site to accommodate the product. This structural change lowers the activations energy and increases the rate of the reaction. The active site changes its shape until an enzyme-substrate complex is formed and activated.