Answer:
The main function of the RB protein is to inhibit the transition from the G1 to S phase. Its activity depends on its phosphorylation state: if RB is not phosphorylated (active state), it is bound to the transcription factor E2F, preventing its translocation to the nucleus and the activation of genes necessary for DNA synthesis; and if it is phosphorylated, by cyclin-CDK complexes, E2F is released and cell proliferation occurs.
Explanation:
Retinoblastoma (Rb) was the first tumor suppressor described and, as we know today, mutations in its structure determine a large number of cancers. Structurally, we speak of a large and multifunctional protein; which is organized in different domains. The activity of this protein is regulated, mainly, by phosphorylation at multiple sites described over the years and is involved in control mechanisms of the cell cycle, apoptosis and senescence.
The offspring that can be described by the genotype is
Gg while for the phenotype is
green pod color
The cross between GG and gg give a heterozygous offspring that Gg offspring. The offspring are have a green pod color since the green pod color is dominant over yellow pod color and therefore the offspring have a green pod color. The cross is as the punnet square below.
A bad line measurement (aka control) is set up so that you can compare your results from each test against so it gives the values a meaning as it shows how they differ from eachother
Anton van Leeuwenhoek :-))
Answer:
Explanation:
When osteocytes were experimentally destroyed, the bones showed a significant increase in bone resorption, decreased bone formation, trabecular bone loss, and loss of response to unloading. ... The osteocyte is an important regulator of bone mass and a key endocrine regulator of phosphate metabolism.
