Mendel's law of independent assortment is about the random distribution of alleles of one gene during anaphase-I. It states that alleles of two or more genes segregate randomly to the poles of the cell. For example, the segregation of R and r alleles to the two poles of the cell would not affect the segregation of the T and t alleles. This random and independent segregation of alleles of different genes during anaphase-I produces new gene combinations in the progeny.