Question

On e theory about the development of neurocognitive disorder due to Alzheimer’s disease suggests that the formatio n of solid waxy proteins in the brain causes the disorder in a process similar to

Answer 1

Answer and Explanation:

  Alzheimer's disease (AD) is a neurodegenerative disease probably caused by the accumulation of beta-amyloid peptide in the brain. AD is the leading cause of dementia in the elderly people. Usually presents with gradual symptoms of loss of cognitive functions (memory, orientation, attention and language) caused by the death of neurons.  

  Similar to AD, we have Lewy body dementia and Parkinson's disease dementia, which may be variations of the same disease. In this disease, synuclein (a protein in the brain that helps nerve cells to communicate) changes shape (remains "badly folded") and slowly accumulates mainly in the brain, but also in the digestive tract and heart. These abnormal synuclein deposits are called Lewy bodies. Misfolded synuclein in Lewy bodies triggers more misfolded synuclein, resulting in the formation of more Lewy bodies. Brain damage results from the accumulation of Lewy bodies. Lewy bodies also is develop in some people with Alzheimer's disease,