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Vera_Pavlovna [14]
3 years ago
8

A client is undergoing a diagnostic workup to rule out multiple myeloma. Which diagnostic findings would confirm the diagnosis o

f multiple myeloma?
Health
1 answer:
prohojiy [21]3 years ago
5 0

Answer:

Plasma cells greater than 10% on bone marrow biopsy

Explanation:

Multiple myeloma is a bone marrow cancer that, for now, has no cure, but a treatment that allows long periods of remission.

Multiple myeloma is a cancer that appears in plasma cells, a type of white blood cell that occurs in the bone marrow. The bone marrow is the spongy material found in the center of the largest bones in the body, and it is also where all blood cells are produced.

One of the tests to diagnose multiple myeloma is Bone Marrow Biopsy

It consists of placing a needle inside the bone to take a small sample of bone marrow, usually in the hip bone. The sample obtained is usually called bone marrow aspirate.

This test includes the plasma cell count and is performed both at the beginning and at the end of the treatment. If the plasma cells is greater than 10 % confirm the diagnosis of multiple myeloma.

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Maximum heart rate is the highest heart rate a healthy person can achieve without experiencing severe problems related to exercise stress. Once you determine your maximum rate, doctors recommend you exercise in your “target heart rate zone,” typically at 60% to 80% of your maximum heart rate for a healthy adult.

Children, however, generally have a higher resting heart rate than adults because they have a smaller heart size, decreased stroke volume, and decreased blood volume. These characteristics throw off the formula and make it inaccurate for children, Dr. Zahka says.

Typically, children ages 6 to 18 tend to have lower maximum heart rates than the formula would indicate, often measuring as low as 185. However, maximums for children can climb as high as 215, he says. The actual heart rate varies by child and is likely genetically determined.

Your doctor can pinpoint your child’s actual maximum heart rate with a formal exercise test, if necessary.

Why does the difference matter?

Knowing that some children have lower maximum heart rates than others could change how schools conduct certain fitness tests, Dr. Zahka says.

Currently, for example, some fitness tests require students to reach 70% of their maximum heart rate.

For a 10-year-old, under the common formula, that means a target heart rate zone of 170 for exercise. But, if a child is genetically predisposed to a maximum heart rate of 180, he should aim for 70% of that, which is only slightly more than 140.

Gender also is a factor for exercise at certain ages, Dr. Zahka says.

Data shows that, at a young age, there’s very little difference in maximum heart rates between boys and girls. That doesn’t change much in adolescence, but it does impact exercise capacity. Between ages 10 and 18, a boy’s ability to exercise harder can increase up to 20%.

What happens when a child pushes too hard?

Pushing your heart rate up too high is dangerous, Dr. Zahka says. It can cause dizziness and shortness of breath. Exercising at or beyond the maximum heart rate for too long can also cause a burning sensation in the muscles due to a buildup of lactic acid.

A child who has these symptoms does not necessarily have an underlying heart or lung problem, Dr. Zahka says. But signs like these show that he is working beyond his abilities that day under those conditions.

Overall, children are typically good self-regulators — unlike adults, who will sometimes push themselves too hard and raise their heart rates dangerously high, Dr. Zahka says.

“Most children under most circumstances will limit themselves appropriately with exercise,” he says. “They’ll slow down or stop when they need to. The important thing is that they know to listen to their bodies.”

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