Making an atom or a virus structure
The law of conservation of mass or principle of mass conservation states that for any system closed to all transfers of matter and energy, the mass of the system must remain constant over time, as system's mass cannot change, so quantity cannot be added nor removed. Hence, the quantity of mass is conserved over time.
The law implies that mass can neither be created nor destroyed, although it may be rearranged in space, or the entities associated with it may be changed in form. For example, in chemical reactions, the mass of the chemical components before the reaction is equal to the mass of the components after the reaction. Thus, during any chemical reaction and low-energy thermodynamic processes in an isolated system, the total mass of the reactants, or starting materials, must be equal to the mass of the products.
According to the Law of Conservation, all atoms of the reactant(s) must equal the atoms of the product(s).
As a result, we need to balance chemical equations. We do this by adding in coefficients to the reactants and/or products. The compound(s) itself/themselves DOES NOT CHANGE.
Answer to this is Radioactive isotopes.
Isotopes are the species of the same element having different atomic masses that means the number of protons remains the same but number of neutrons do differ. For example
and
are the two isotopes of Hydrogen (
).
Radioactive isotopes are the isotopes which release some kind of energy in the form of alpha particles, beta particles or gamma radiation. Examples of each of the decay processes are :
Alpha Decay: In this decay one alpha particle having atomic mass 4 and atomic number 2 or we can say a He molecule will come out. 
Beta Decay: In this decay a
particle is emitted increasing the atomic number of the reactant by 1 unit.

Gamma Radiation: In this type of reaction only radiation is emitted out which does not change the original molecule.

Answer:
C. Particle size
Explanation:
The sand, which has smaller particles, will go through the sieve, while the rice (with a larger particle size) will not