Question

CH3CH2PH2 can be synthesized by an SN2 reaction. Draw the structures of the alkyl chloride and nucleophile that will give this compound in highest yield. Use the wedge/hash bond tools to indicate stereochemistry where it exists. Include all valence lone pairs in your answer. Separate multiple reactants using the + sign from the drop-down menu. When a metal counterion is needed, use Na+, but draw it in its own sketcher.

Answer 1

Answer:

The PH2 becomes attached to the alkyl halide with inversion of configuration

Explanation:

SN2 reaction involves the simultaneous attachment of the nucleophile as the leaving group departs. This leads to an inversion of configuration because the sterochemistry around the carbon bearing the leaving group is reversed. The reaction proceed via a crowded five coordinate transition state. Details are shown in the image attached.