Question

What changes in fatty acid metabolism would result from a mutation in the muscle carnitine acyltransferase i in which the mutant protein has lost its affinity for malonyl-coa but not its catalytic activity?

Answer 1

The metabolism of a fatty acid comprises catabolic procedures, which produce energy and anabolic procedures that generate biologically essential molecules. The fatty acids belong to a family of molecules categorized within the lipid macronutrient class. One function of fatty acids in animal metabolism is the production of energy in the form of ATP.

The correct answer of the question is option B, that is, fatty acid synthesis in the cytosol and oxidation of fatty acid in the mitochondria could take place simultaneously because due to mutation, malonyl-CoA would no longer prevent the admittance of fatty acid into the mitochondria and would undergo the process of beta-oxidation.