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Salsk061 [2.6K]
3 years ago
10

Amantadine is effective in preventing infections caused by the influenza A virus and in treating established illnesses. It is th

ought to block a late stage in the assembly of the virus. Amantadine is synthesized by treating 1-bromoadamantane with acetonitrile in sulfuric acid to give N-adamantylacetamide, which is then converted to amantadine.
(a) Propose a mechanism for the transformation in Step 1.
(b) Describe experimental conditions to bring about Step 2.

Chemistry
1 answer:
Sliva [168]3 years ago
7 0

Answer:

See image attached

Explanation:

a)

The full reaction mechanism of step 1 was obtained from Bartleby and attached to this answer. The steps involved in the reaction are:

1) Loss of Br- and formation of a carbocation

2) Attack of CH3CN on the carbocation

4) Formation of a quaternary nitrogen intermediate

5) Attack of water on the quaternary nitrogen intermediate

6) Loss of the water molecule

5) Formation of the amide product

b)

i) sodium hydroxide

ii) HCl

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What is the Net Ionic equation for this chemical reaction: FeBr2+Na2S=FeS+2NaBr​
Artyom0805 [142]

Answer: Fe<em>(aq)</em>+S<em>(aq)</em>=FeS<em>(s)</em>

Explanation: The Sodium and Bromine are spectator ions because they don't react with anything, you can see this by writing the ionic equation like so:

1.) Molecular formula (given): FeBr2 (aq)+Na2S (aq)= FeS(s)+2NaBr(aq)

Each dissolved FeBr2 breaks up into one Fe with a charge of 2+ and two Br with a negative charge. This gives you:

Fe(aq)+ 2Br(aq)+Na2S(aq)=FeS(s)+2NaBr

2.) Now repeat what was shown with the other compounds in the given molecular formula, and pay attention to the states that each ion is in (solid, liquid, aqueous, gas) because this will give you the ionic equation, which from there you can get rid of any ions that don't change amount or state.

3.) Ionic formula: Fe(aq)+ <u>2Br(aq)</u>+<u>2 Na(aq)</u>+S (aq)=FeS(s)+<u>2 Na(aq)+2Br(aq)</u>

4.)When you've derived a total ionic equation (above), you'll  find that some ions appear on both sides of the equation in equal numbers. For example, in this case two Na cations and two Br anions appear on both sides of the total ionic equation. What does this mean? It means these ions don't participate in the chemical reaction. They're present before and after the reaction. Nothing happens to them. So those are removed and you're left with the net ionic: Fe(aq)+S(aq)=FeS(s)

Hope this helps :)

7 0
3 years ago
Giving brain thing.
Over [174]
I think the correct answer is C
7 0
3 years ago
If the bag was made from a metal (like sturdy aluminum foil), do you think it would lose its heat faster or slower than the plas
Iteru [2.4K]

Answer:

Fish

Explanation:

Because fish and why fish? because fish was one fish so i know this answer is 11

3 0
2 years ago
Given that the formula of butane C4H10 the accepted value for the molar mass should be
deff fn [24]

Answer:

carbon mass = 12.01g/mol

hydrogen mass = 1.01g/mol

4 carbon atoms and 10 hydrogen so

12.01 x 4 + 1.01 x 10

48.04g/mol + 10.10g/mol

= 58.14g/mol

4 0
2 years ago
Benzoic acid, c6h5cooh, has a ka = 6.4 x 10-5. what is the concentration of h3o+ in a 0.5 m solution of benzoic acid? 3.2 x 10-5
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The answer for this issue is: 
The chemical equation is: HBz + H2O <- - > H3O+ + Bz- 
Ka = 6.4X10^-5 = [H3O+][Bz-]/[HBz] 
Let x = [H3O+] = [Bz-], and [HBz] = 0.5 - x. 
Accept that x is little contrasted with 0.5 M. At that point, 
Ka = 6.4X10^-5 = x^2/0.5 
x = [H3O+] = 5.6X10^-3 M 
pH = 2.25
(x is without a doubt little contrasted with 0.5, so the presumption above was OK to make) 
3 0
3 years ago
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