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Salsk061 [2.6K]
3 years ago
10

Amantadine is effective in preventing infections caused by the influenza A virus and in treating established illnesses. It is th

ought to block a late stage in the assembly of the virus. Amantadine is synthesized by treating 1-bromoadamantane with acetonitrile in sulfuric acid to give N-adamantylacetamide, which is then converted to amantadine.
(a) Propose a mechanism for the transformation in Step 1.
(b) Describe experimental conditions to bring about Step 2.

Chemistry
1 answer:
Sliva [168]3 years ago
7 0

Answer:

See image attached

Explanation:

a)

The full reaction mechanism of step 1 was obtained from Bartleby and attached to this answer. The steps involved in the reaction are:

1) Loss of Br- and formation of a carbocation

2) Attack of CH3CN on the carbocation

4) Formation of a quaternary nitrogen intermediate

5) Attack of water on the quaternary nitrogen intermediate

6) Loss of the water molecule

5) Formation of the amide product

b)

i) sodium hydroxide

ii) HCl

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Answer:

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Explanation:

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Can someone help me with this please
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(Please help, ASAP) How many grams are in 3.45x10^23 atoms of P?
Daniel [21]

one mole of P weights about 31 grams

in one mole there are 6.022*10^23 atoms

we use the rule of threes

6.022*10^23atoms......weight..........31 grams

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x=(3.45*10^23*31)/6.022*10^23

x=106.95/6.022=<u><em>17.76 grams</em></u>

5 0
3 years ago
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3 years ago
If you performed this experiment using mgcl2 as the solute would the molar concentration of mgcl2 that is isotonic to the potato
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5 0
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