Answer:
a. substantia nigra
b. substantia nigra (it is repeated)
Explanation:
Parkinson's disease is a neurodegenerative disease that is caused by the death of neurons that release the neurotransmitter dopamine in the <u>substantia nigra</u>, or locus niger, -a region of the brain that regulates brain circuits that give the 'orders' to initiate voluntary movements- .
The lack of this neurotransmitter leads to the occurrence of the main symptoms suffered by patients: decreased movements, muscle stiffness, postural instability and tremor. These failures are generated by the abnormal way in which neurons work in the absence of dopamine through a mechanism that is not known in depth.
It is the second most frequent neurodegenerative disease, after Alzheimer's disease, with a prevalence of 2% in people over 65 years. The characteristic symptoms of stiffness, bradykinesia and tremor are associated with losses of neurons in the substantia nigra and dopamine depletion in the striatum. There are large cytoplasmic inclusions, called Lewy bodies, which are the pathological mark of the disease and appear predominantly in neurons that contain melanin of the nigra substance. Genetic studies in a subgroup of families with Parkinson's disease with autosomal dominant inheritance found a locus on chromosome 4q-21 23 and a mutation in the gene that encodes a synaptic protein, α-synuclein.
Answer:
Explanation:
A tissue is a group of similar cells that work together to do a particular job. For example, most animals have muscle tissues, which are made up of muscle cells.
Answer:
Chloroplasts are what give plants their green color. The second major difference between plant and animal cells is the cell wall. While both plant and animal cells have a cell membrane, on plants have a cell wall.
Step 1: Glycolysis. In glycolysis, glucose—a six-carbon sugar—undergoes a series of chemical transformations. In the end, it gets converted into two molecules of pyruvate, a three-carbon organic molecule. In these reactions, ATP is made, and \text{NAD}^+NAD + N, A, D, superscript is converted to {NADH}NADHN, A, D, H.
Step 2:Pyruvate oxidation. Each pyruvate from glycolysis goes into the mitochondrial matrix—the innermost compartment of mitochondria. There, it’s converted into a two-carbon molecule bound to Co-enzyme A, known as acetyl CoA. Carbon dioxide is released and NADH is generated.
Step 3:Citric acid cycle. The acetyl CoA made in the last step combines with a four carbon molecule and goes through a cycle or reaction, ultimately regenerating the four carbon starting molecule.
