Question

It is actually the 16S rRNA component of a 30S ribosomal subunit that is responsible for recognition of a Shine-Dalgarno sequence. Which one of the following sequences in the 16S rRNA would you predict is responsible for the interaction between a small subunit and mRNA?
a) 5'-UCCUCCA-3'
b) 5'-UGGAGGA-3'
c) 5'-AGGAGGU-3'
d) 3'-UCCUCCA-5'
e) 3'-UAC-5'

Answer 1

The correct answer is (D)

Explanation:

• The Australian scientists John Shine and Lynn Dalgarno proposed the Shine Dalgarno Sequence.

• The Shine Dalgarno Sequence is found around 8 Bases in upstream of AUG which is a start codon.

• In archaea mRNA and bacteria Shine Dalgarno Sequence is a ribosomal binding site.

• The Shine Dalagarno Sequence is found in archaea and bacteria.

• It is also seen in Mitochondrial transcripts and Chloroplast.