Explanation:
Medicinal chemistry and pharmaceutical chemistry are disciplines at the intersection ofchemistry, especially synthetic organicchemistry, and pharmacology and various other biological specialties, where they are involved with design,chemical synthesis and development for market of pharmaceutical agents, or bio-active ...
Answer:
Explanation:
(a) Part 1:
reaction. This is a nucleophilic substitution reaction in which we have two steps. Firstly, chlorine, a good leaving group, leaves the carbon skeleton to form a relatively stable secondary carbocation. This carbocation is then attacked by the hydroxide anion, our nucleophile, to form the final product.
To summarize, this mechanism takes places in two separate steps. The mechanism is attached below.
Part 2:
reaction. This is a nucleophilic substitution reaction in which we have one step. Our nucleophile, hydroxide, attacks the carbon and then chlorine leaves simultaneously without an intermediate carbocation being formed.
The mechanism is attached as well.
(b) The rate determining step is the slow step. Formation of the carbocation has the greatest activation energy, so this is our rate determining step for
. For
, we only have one step, so the rate determining step is the attack of the nucleophile and the loss of the leaving group.
Range means the difference between the highest and lowest number. So subtract 25 - 14 which gives you 11.
Atomic number is same as the number of protons in the element which is further equal to the number of electrons. As the number of electrons increases in the element, the atomic number of the element also increases.
In periodic table, elements are arranged in the groups, and these groups are columns starting from 1 to 18, elements are arranged in increasing order of atomic number. Elements are placed with difference of one atomic number.
First four elements present in the periodic table is:
atomic number is one (1).
atomic number is two (2).
atomic number is three (3).
atomic number is four (4).
Thus, the series of atomic numbers that represents the ordering of consecutive elements within the periodic table is the last option - 1, 2, 3, 4...
If I heat a reaction then the rate will increase because the higher the temperature the faster the reaction.
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