The coefficients of the substances give you the ratio of the number of moles. The 4 before the H2O and the 5 before the HCl tell you that for every 5 moles of HCl created, 4 moles of H2O had to react.
Therefore: can be used to find the moles of H2O that react.
The least electronegative component in the electron transport chain is the Hydrogen ion. The more electronegative is NAD+ The other component is H2O, Next are the energy carrier molecules which are the ADP and ATP And finally, the most electronegative is O2.