A group of Chinese women with PCOS who were receiving treatment saw several metabolic and hormonal imbalances improve after taking BBR. The primary consequences may be connected to the modifications in body composition in obesity and dyslipidemia. For the evaluation of the possible beneficial metabolic effects of BBR in women with PCOS, additional controlled trials are required.
PCOS:
- Objective: Insulin resistance is a common metabolic and reproductive condition called polycystic ovarian syndrome (PCOS) (IR). A quinoline derivative alkaloid known as berberine (BBR) has been utilized as an insulin sensitizer and is isolated from Chinese medicinal herbs. There may be a therapeutic benefit for PCOS from BBR. The purpose of this study was to compare the effects of BBR and metformin (MET) on the metabolic characteristics of PCOS-affected women.
- Design and methods: Ninety nine PCOS and IR patients were randomly assigned to one of three therapy groups: BBR+ compound cyproterone acetate (CPA;
), MET
CPA
, and placebo CPA 
for 
months. Before and after the treatment period, metabolic and hormonal measures as well as the clinical characteristics of the women were evaluated. - Results: Reduced waist circumference, waist-to-hip ratio (WHR;P<
), total cholesterol (TC), triglycerides (TG), and low-density lipoprotein cholesterol (LDLC; P<
), as well as increased levels of high-density lipoprotein cholesterol (HDLC) and sex hormone-binding globulin (SHBG; P<) were all observed following treatment with BBR as compared to MET. Similarly, BBR treatment decreased WHR, fasting plasma glucose, fasting insulin, homeostasis model evaluation for IR, area under the insulin curve, TC, LDLC, and TG (P<), while increasing HDLC and SHBG (P<) as compared to placebo.
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Answer:
Synergism
Explanation:
Synergism means cooperation, and is a term of Greek origin (synergy). Synergy is a work or effort to accomplish a certain very complex task, and to be able to succeed in the end. Synergy is the moment when the whole is greater than the sum of its parts.
In physiology, synergism occurs when the effect of two or more combined chemical agents is greater than the sum of individual effects. Concerning hormones, synergism happens when two hormones must be present for the full expression of an effect. That is, two hormones act for a certain purpose.
Example: FSH (follicle stimulating hormone) and estrogen cause oocyte maturation, but this only occurs if neither acts in isolation.
That is true it can not happen
I would have to say <span>This is an example of incomplete dominance but i'm not sure if correct. </span>
Answer:
The part of the enzyme where the substrate fits is known as the: active site
Explanation:
Enzymes work by bringing reactants together at a higher energy level than they would need in an uncatalyzed reaction.
