The first top one is right
If denaturation occurs (extreme temperature change or pH changes), the enzyme will not be reusable! The structure of the enzymes are not changed. As a result of this, enzymes will be used again and again to bind onto another substrate molecule and catalyze the reaction once again.
for me its glitched or word cut off i see no picture or question :/
73130-26, S62.323A, W51.XXXA, Y93.61 that should help.