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Setler79 [48]
3 years ago
15

dependence upon a drug is characterized by a state of mental and physical abnormality when the drug is withdrawn. dependence is

marked by a craving for the drug.
Health
1 answer:
ryzh [129]3 years ago
7 0

Physical

Psychologica

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Prolong exposure to stress, increases the cortisol production in body. Prolong stress can also cause certain changes to the neurons located in paraventricular nucleus, ultimately resulting in sustained activation of the axis. Long term activation of the axis causes negative feedback mechanism and ultimately causes fatigue, exhaustion, headache and depression etc.  

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