Answer:
300,000 years ago
Explanation:
Homo sapiens evolved from their early hominid predecessors between 200,000 and 300,000 years ago and developed a capacity for language about 50,000 years ago.
Our genes can be affected by the environment and change the way our traits are displayed, called the phenotype. However, changes in phenotype have an underlying genotypic source. Epigenetics or epigenetic changes are changes in the way traits are expressed as an effect of the environment (i.e. food we ate, chemicals in the body, environmental stresses), without changes in the DNA. Simply put, in epigenetics, some parts of the DNA are turned on or off in response to environmental conditions.
Organelles must do their duties together and their activities must be coordinated I'm pretty sure.